Electrical fields in wound healing-An overriding signal that directs cell migration.
Published in Seminars in cell & developmental biology
Injury that disrupts an epithelial layer instantaneously generates endogenous electric fields (EFs), which were detected at human skin wounds over 150 years ago. Recent researches combining molecular, genetic and imaging techniques have provided significant insights into cellular and molecular responses to this "unconventional" signal. One unexpect...