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Polarizing intestinal epithelial cells electrically through Ror2.

Cao, L Mccaig, Cd Scott, Rh Zhao, S Milne, G Clevers, H Min Zhao Pu, J

Published in Journal of Cell Science

The apicobasal polarity of enterocytes determines where the brush border membrane (apical membrane) will form, but how this apical membrane faces the lumen is not well understood. The electrical signal across the epithelium could serve as a coordinating cue, orienting and polarizing enterocytes. Here, we show that applying a physiological electric ...

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