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PI3K mediated electrotaxis of embryonic and adult neural progenitor cells in the presence of growth factors.

Meng, Xiaoting Arocena, Miguel Penninger, Josef Gage, Fred H Zhao, Min Song, Bing

Published in Experimental neurology

Correct guidance of the migration of neural progenitor cells (NPCs) is essential for the development and repair of the central nervous system (CNS). Electric field (EF)-guided migration, electrotaxis, has been observed in many cell types. We report here that, in applied EFs of physiological magnitude, embryonic and adult NPCs show marked electrotax...

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